CTPR: Cross-Trait Penalized Regression

Resources

● All Predictors for human height by aid of BMI with 437K training samples from UK Biobank using PRS, LDpred, MCP, Lasso, PRS+MTAG, LDpred+MTAG, MCP+CTPR and Lasso+CTPR are available from the following link: Link

Citation: Wonil Chung, Jun Chen, Constance Chen, Sara Lindstroem, Zhaozhong Zhu, Po-Ru Loh, Peter Kraft and Liming Liang (2019), Efficient Cross-Trait Penalized Regression Increases Prediction Accuracy in Large Cohorts using Secondary Phenotypes, Nature Communications, 10(1), 569: Link

Links

CTPR Software at GitHub

Wonil Chung at Harvard T.H. Chan School of Public Health

Liming Liang's Lab at Harvard T.H. Chan School of Public Health